Advanced culture systems for ex vivo human vascular tissue conditioning
DOI:
https://doi.org/10.4081/bse.90Keywords:
Advanced culture system, ex vivo bioreactor, human vascular tissue, biomechanical conditioning, 3R principlesAbstract
Our experience shows that using bioengineering approaches facilitates the understanding of vascular physio-pathological mechanisms and, in perspective, will speed up the development of new life-saving treatments. The use of human samples, particularly operating room-derived samples, which would have been otherwise discarded, is a very valuable approach. In line with the 3Rs principles, this methodology is worth the cost of being set up and managed, wherever and whenever possible
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