Stress-induced premature senescence in hiPSC-derived cardiomyocytes recapitulates aging-induced cardiac remodelling

Authors

  • E. Lazzarini Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona
  • A. M. Lodrini Department of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca, Italy; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden
  • M. Arici Department of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca
  • S. Bolis Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona; Cellular and Molecular Cardiology, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona
  • S. Vagni Department of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca
  • S. Panella Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona
  • A. Rendon-Angel Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano
  • M. Saibene Department of Earth and Environmental Sciences, Università degli Studi di Milano-Bicocca, Milano
  • A. Metallo Department of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca
  • T. Torre Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano
  • G. Vassalli Cellular and Molecular Cardiology, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano
  • P. Ameri Cardiovascular Disease Unit, IRCCS Ospedale Policlinico, Genova; Department of Internal Medicine, University of Genova
  • C. Altomare Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona
  • M. Rocchetti Department of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca
  • L. Barile Cardiovascular Theranostics, Istituto Cardiocentro Ticino, Laboratories for Translational Research, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland;Institute of Life Science, Scuola Superiore Sant’Anna, Pisa

DOI:

https://doi.org/10.4081/bse.230

Abstract

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Published

17-11-2023

Issue

Vol. 5 No. 1 (2024)

Section

Original Articles

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Copyright (c) 2023 the Author(s)

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How to Cite

Stress-induced premature senescence in hiPSC-derived cardiomyocytes recapitulates aging-induced cardiac remodelling. (2023). Biomedical Science and Engineering, 5(1). https://doi.org/10.4081/bse.230