Polyvinyl alcohol/cellulose hydrogel as possible corneal stroma substitute in drug permeation tests

Authors

  • Erica Zucchetti Department of Pharmacy, University of Pisa, Pisa
  • Leonardo Ling Department of Pharmacy, University of Pisa, Pisa
  • Daniela Monti Department of Pharmacy, University of Pisa, Pisa; Italian inter-university centre for the promotion of the 3Rs in teaching and research, Pisa
  • Patrizia Chetoni Department of Pharmacy, University of Pisa, Pisa; Italian inter-university centre for the promotion of the 3Rs in teaching and research, Pisa
  • Silvia Tampucci Department of Pharmacy, University of Pisa, Pisa; Italian inter-university centre for the promotion of the 3Rs in teaching and research, Pisa
  • Susi Burgalassi Department of Pharmacy, University of Pisa, Pisa; Italian inter-university centre for the promotion of the 3Rs in teaching and research, Pisa

DOI:

https://doi.org/10.4081/bse.203

Keywords:

Permeation studies, cornea, stroma equivalent, epithelial tissue, hydrogel

Abstract

The permeation studies of active compounds and formulations are necessary to verify the capability of molecules to pass through the physiological barrier of our body. In order to develop a 3D model of the cornea, preparation and characterization of different hydrogels as corneal stroma substitutes were tested.

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Published

29-09-2021

Issue

Vol. 2 No. 1 (2021)

Section

Communications

License

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

Polyvinyl alcohol/cellulose hydrogel as possible corneal stroma substitute in drug permeation tests. (2021). Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.203