Electrostimulation of a 3D in vitro skin model to activate wound healing

Authors

  • Simona Villata Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin, Italy
  • Lucia Napione Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin
  • Désirée Baruffaldi Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin
  • Christine Nardini IAC Institute for Applied Computing, Consiglio Nazionale delle Ricerche (CNR), Rome
  • Francesca Frascella Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin
  • Fabrizio Pirri Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, Turin; PolitoBIOMed Lab, Politecnico di Torino, Turin

DOI:

https://doi.org/10.4081/bse.200

Keywords:

Skin model, in vitro model, wound healing, electrostimulation

Abstract

The aim of the work is to propose a methodology for the stimulation of a 3D in vitro skin model to activate wound healing. The presented work is in the frame of the national research project, CronXCov, "Checking the CHRONIC to prevent COVID-19", devoted to understand how physiologic and inflamed skin on chip 3D models evolve upon a range of physical (e.g., electrical, mechanical, optical) stimulations, over time. Thanks to the 3D modelling, using Next Generation Sequencing and the network medicine frame of analysis to process the data, we will systematically characterize the effects of the applied stimuli, offering new insight for the exploitation of wound healing.

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Published

29-09-2021

Issue

Vol. 2 No. 1 (2021)

Section

Communications

License

Copyright (c) 2021 The Authors

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

Electrostimulation of a 3D in vitro skin model to activate wound healing . (2021). Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.200