Promising 3D in vitro models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer

Authors

  • Stefania Forciniti Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce; Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona
  • Marta Cavo Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce
  • Ilaria Dando Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona
  • Elisa Dalla Pozza Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona
  • Marta Palmieri Department of Neurosciences, Biomedicine and Movement Sciences, Biochemistry Section, University of Verona
  • Loretta L. del Mercato Institute of Nanotechnology, National Research Council (CNR-NANOTEC), Lecce

DOI:

https://doi.org/10.4081/bse.169

Keywords:

3D tumour models, cancer stem cells, tumour microenvironment, pancreatic ductal adenocarcinoma

Abstract

In this study we produced 3D organotypic cultures and spheroids to mimic the complex microenvironment of pancreatic cancer and to test alternative therapeutic strategies.

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Published

29-09-2021

Issue

Vol. 2 No. 1 (2021)

Section

Communications

License

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

Promising 3D in vitro models for studying tumour heterogeneity and testing novel therapeutic approaches in pancreatic cancer. (2021). Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.169