An osteochondral bio-engineered model to in vitro mimicking osteoarthritis

Authors

  • Giorgia Cerqueni Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona
  • Annachiara Scalzone School of Engineering, Newcastle University, Newcastle upon Tyne
  • Xiao Nong Wang Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne
  • Caterina Licini Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona
  • Kenny Dalgarno School of Engineering, Newcastle University, Newcastle upon Tyne
  • Ana Marina Ferreira-Duarte School of Engineering, Newcastle University, Newcastle upon Tyne
  • Piergiorgio Gentile School of Engineering, Newcastle University, Newcastle upon Tyne
  • Monica Mattioli Belmonte Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona

DOI:

https://doi.org/10.4081/bse.162

Keywords:

Osteoarthritis in-vitro model, GellanGum, 3D printing, inflammation

Abstract

To date, treatments of Osteoarthritis are not able to provide the pathology regression. In vitro models are therefore necessary to: i) investigate the mechanisms involved in the disease evolution, ii) identify pharmacological targets, and iii) perform predictive tests for new drug delivery strategies.

Downloads

Download data is not yet available.

References

Downloads

Published

29-09-2021

Issue

Vol. 2 No. 1 (2021)

Section

Communications

License

Copyright (c) 2021 The Authors

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

An osteochondral bio-engineered model to in vitro mimicking osteoarthritis . (2021). Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.162