3F(eature)s model: modularity, heterogeneity and three-dimensionality to design in vitro neuronal model

Authors

  • Martina Brofiga Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS) University of Genova, Genova
  • Marietta Pisano Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS) University of Genova, Genova
  • Mariateresa Tedesco Brain AG
  • Francesca Callegari Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS) University of Genova, Genova
  • Paolo Massobrio Department of Informatics, Bioengineering, Robotics and Systems Engineering (DIBRIS) University of Genova, Genova; National Institute for Nuclear Physics (INFN), Genova

DOI:

https://doi.org/10.4081/bse.158

Keywords:

Cortex, hippocampus, modularity, heterogeneity, three-dimensionality

Abstract

In this work, we present a novel experimental platform to build in vitro interconnected (i.e., modular) heterogeneous (e.g., cortical-hippocampal) and three-dimensional (3D) neuronal cultures plated on Micro-Electrode Arrays (MEAs) to extracellularly record the electrophysiological activity continuously.

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Published

29-09-2021

Issue

Vol. 2 No. 1 (2021)

Section

Communications

License

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

3F(eature)s model: modularity, heterogeneity and three-dimensionality to design in vitro neuronal model. (2021). Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.158