Superoxide dismutase 1 (SOD1) and cadmium: a three models approach to the comprehension of its neurotoxic effects

Authors

  • Federica Bovio Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy, Milan
  • Barbara Sciandrone Department of Biotechnology and Biosciences, University of Milano- Bicocca, Italy, Milan
  • Chiara Urani Department of Earth and Environmental Sciences, University of Milan Bicocca, Milan, Italy; Integrated Models for Prevention and Protection in Environmental and Occupational Health, (MISTRAL), Interuniversity Research Center
  • Paola Fusi Department of Biotechnology and Biosciences, University of Milano- Bicocca, Italy, Milan; Integrated Models for Prevention and Protection in Environmental and Occupational Health, (MISTRAL), Interuniversity Research Center
  • Matilde Forcella Department of Biotechnology and Biosciences, University of Milano- Bicocca, Italy, Milan
  • Maria Elena Regonesi Department of Biotechnology and Biosciences, University of Milano- Bicocca, Italy, Milan; Milan Center of Neuroscience (NeuroMI), Milan

DOI:

https://doi.org/10.4081/bse.157

Keywords:

Cadmium, SOD1, E. coli, SH-SY5Y neuronal cells, Caenorhabditis elegans

Abstract

In three different biological models, the recombinant protein expressed in E. coli, the neuronal cells SH-SY5Y and the nematode Caenorhabditis elegans, cadmium inhibits SOD1 activity without affecting its expression level.

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Published

29-09-2021

Issue

Vol. 2 No. 1 (2021)

Section

Communications

License

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

Superoxide dismutase 1 (SOD1) and cadmium: a three models approach to the comprehension of its neurotoxic effects. (2021). Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.157