A novel in silico tool for dose assessment in cell culture nanotoxicology

Authors

  • Ermes Botte Research Centre “E. Piaggio”, University of Pisa; Department of Information Engineering, University of Pisa
  • Pietro Vagaggini Research Centre “E. Piaggio”, University of Pisa
  • Joana Costa Research Centre “E. Piaggio”, University of Pisa
  • Lara Faccani Institute of Science and Technology for Ceramics, CNR, Faenza
  • Ilaria Zanoni Institute of Science and Technology for Ceramics, CNR, Faenza
  • Anna Costa Institute of Science and Technology for Ceramics, CNR, Faenza
  • Arti Ahluwalia Research Centre “E. Piaggio”, University of Pisa; Department of Information Engineering, University of Pisa

DOI:

https://doi.org/10.4081/bse.156

Keywords:

In silico modelling, ENMs, in vitro dosimetry

Abstract

Dose assessment is essential for understanding the mechanisms triggering nanomaterial toxicity in vitro and for meaningful translations to in vivo. We propose a novel computational approach for improving the accuracy of biological dose-response characterization, demonstrating its robustness for insoluble Engineered Nanomaterials (ENMs).

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Published

29-09-2021

Issue

Vol. 2 No. 1 (2021)

Section

Communications

License

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

A novel in silico tool for dose assessment in cell culture nanotoxicology. (2021). Biomedical Science and Engineering, 2(1). https://doi.org/10.4081/bse.156