A viability study of 3D tumor spheroids after their mass-density characterization via an innovative flow-based biophysical method

Authors

  • Francesco Bacchi CellDynamics isrl, Bologna, Italy
  • Azzurra Sargenti CellDynamics isrl, Bologna
  • Francesco Musmeci CellDynamics isrl, Bologna
  • Simone Pasqua CellDynamics isrl, Bologna
  • Simone Bonetti CellDynamics isrl, Bologna
  • Daniele Gazzola CellDynamics isrl, Bologna
  • Domenico Andrea Cristaldi CellDynamics isrl, Bologna

DOI:

https://doi.org/10.4081/bse.140

Keywords:

Spheroids, organoids, 3D cell culture, viability, biophysics

Abstract

The simple measurement of mass density, size and weight of sphere-like 3D cell models has been recently enabled by a specifically conceived flow-based method. Here we demonstrate that such technique also allows the post-analysis collection of live 3D tumor spheroids, without compromising their viability.

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Published

28-09-2021

Issue

Vol. 3 No. 1 (2022)

Section

Original articles

License

Copyright (c) 2021 The Authors

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.

How to Cite

A viability study of 3D tumor spheroids after their mass-density characterization via an innovative flow-based biophysical method . (2021). Biomedical Science and Engineering, 3(1). https://doi.org/10.4081/bse.140