A millifluidic-based 3D-platform as a useful tool for the efficacy of glaucoma therapeutic strategies

Authors

  • Anna M. Bassi Department of Experimental Medicine (DIMES), University of Genoa; Inter-University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Pisa
  • Sara Tirendi Department of Experimental Medicine (DIMES), University of Genoa; Inter- University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Pisa
  • Sonia Scarfì Inter- University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Pisa; Department of Earth, Environment and Life Sciences (DISTAV), University of Genoa
  • Mario Passalacqua Department of Experimental Medicine (DIMES), University of Genoa; Inter- University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Pisa
  • Vanessa Almonti Department of Experimental Medicine (DIMES), University of Genoa; Inter- University Center for the Promotion of the 3Rs Principles in Teaching & Research (Centro 3R), Pi
  • Stefania Vernazza Department of Experimental Medicine (DIMES), University of Genoa

DOI:

https://doi.org/10.4081/bse.135

Keywords:

Glaucoma, in vitro model, trabecular meshwork

Abstract

The aim of this present study is to investigate the role of damaged Trabecular Meshwork (TM) in triggering neuron-like cell apoptosis. Preliminary results showed that stressed TM releases harmful signals to neuron-like cells, suggesting its pivotal role in glaucoma cascade.

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Published

28-09-2021

Issue

Vol. 3 No. 1 (2022)

Section

Original articles

License

Copyright (c) 2021 the Authors

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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How to Cite

A millifluidic-based 3D-platform as a useful tool for the efficacy of glaucoma therapeutic strategies. (2021). Biomedical Science and Engineering, 3(1). https://doi.org/10.4081/bse.135